Topical corticosteroids have been available for more than six decades during which they have completely changed the face of therapy of dermatological disorders Despite being the most useful drug for such treatment they are known to produce serious local, systemic and psychological side-effects when overused or misused A separate book dedicated to topical corticosteroids has never been planned or executed This treatise aims to fill up the lacuna and to contribute significantly to the dissemination of knowledge about the indication/contraindication, mechanism of action, ethical use, side-effects and various other facets related to topical corticosteroid. Topical corticosteroids (TC) have greatly enhanced dermatologists’ ability to effectively treat several difficult dermatoses. The available range of formulations and potencies allows them to flexibly treat all groups of patients, different phases of the disease, and different anatomic sites.