Presents the daily clinical practice setting of high-risk patients with hypertension-related kidney damage In-depth review of antihypertensive treatments in highly comorbid patients – with a particular focus on RAAS inhibitors and combination treatment Reviews and discusses current guidelines on the evaluation and treatment of patients with hypertension and renal dysfunction This book guides readers through a wide spectrum of clinical presentations in patients with arterial hypertension and different degrees of renal impairment, ranging from asymptomatic urine abnormalities to end-stage renal disease. Based on six case studies, the author reviews and discusses current guidelines and recommendations aimed at optimizing the diagnostic and therapeutic approach both to renal and cardiovascular risk in commonly encountered real-world clinical scenarios including challenging cases of diabetic kidney disease, ischemic nephropathy, and resistant hypertension.