Outlines indications for use of IgG concentrates and other modern immunomodulators Reviews basic aspects of IgG concentrates Provides an update on immunomodulatory IgG treatment in ITP Examines mAbs as immunomodulators and anticancer agents This practical manual, written by well-known experts, reviews current indications for the use of IgG concentrates and some other modern immunomodulators and provides fundamental information on present-day immunomodulation in patients (and mice). The book opens by tracing the transition from IgG substitution to IgG immunomodulation and providing expert updates on immunomodulatory indications in autoimmune and inflammatory disorders, including hematologic, neurologic, dermatologic, and other diseases. Basic aspects of IgG concentrates, including methods of production, safety, currently available products, and mechanisms of action, are then discussed.